logica endocrino HCtcl Diabetes and Diabetes Treatment IV Supplementum 272 NORDISK SYMPOSIUM Editor: Esko Nikkilä VOlUfTlG 1 IL) 1

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1 NORDISK SYMPOSIUM Diabetes and Diabetes Treatment IV Editor: Esko Nikkilä HCtcl endocrino logica Supplementum 272 ISSN ACEDAS (1985) - VOlUfTlG 1 IL) 1

2 NORDISK SYMPOSIUM Diabetes and Diabetes Treatment IV Diabetes and Atherosclerosis Optimal Insulin Therapy Factors affecting Diabetic Control Edited by E. Nikkilä Sponsored by NORDISK GENTOFTE Vs and held at Tampere University Central Hospital, Finland October 27-29, 1983

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4 List of Contributors A. Aro. M.D. National Public Health Institute Mannerheimintie 166 Helsinki, Finland O. Faber, M.D. Frederiksborg County Hospital H0rsholm, Denmark K. Hanssen, M.D. Medical Department Aker Hospital Oslo, Norway R. Jarrett, Professor, M.D. Department of Community Medicine Guy's Hospital Medical Schol London, U.K. J. Jervell, M.D., Docent University Clinic Oslo, Norway T. Lauritzen, M.D. Osterallé 14 Ebeltoft, Denmark J. Ludvigsson, Professor, M.D. Department of Pediatrics University Hospital Linköping Hospital Linköping, Sweden J. Nerup, M.D. Steno Memorial Hospital Gentofte, Denmark E. Nikkilä, Professor, M.D. Third University Hospital Helsinki, Finland R. Pelkonen, Professor, M.D. Third The Endocrine Unit University of Helsinki Helsinki, Finland K. Pyörälä, Professor, M.D. University of Kuopio Kuopio, Finland L. Viinikka, M.D. Laboratory of Children's Hospital University of Helsinki Helsinki. Finland J. Östman, M.D., Docent Huddinge Hospital Huddinge, Sweden

5 Participants Oystein Aagenœs, Oslo Sylvi Aanderud, Troms0 Jens Olai Alvsaker, Oslo Katri Annoia, Helsinki Antti Aro, Helsinki Ole Artved, Viborg Vivian H. Asfeldt, Herning Haakon Barkve, Stavanger Ingmar Bergström, Östersund Göran BIohmé, Göteborg Peter Christiansen, NaiStved Poul Dan0, Helsing0r Göran Ekberg, Malmö Lars Engström, Sundsvall Bernard Enk, Nyk0bing Falster Ole Faber, H0rsholm Peer Klose Frederiksen, Nyk0bing Mors Thorkild Friis, Frederiksberg Gunilla Gillnäs, Boden Gunnar Gregersen, Esbjerg Leif Groop, Helsinki Folke Gyland, Landskrona Hannu Haapamäki, Lahti Jens Haarstad, Namsos Kristian F. Hanssen, Oslo Kari Harno, Helsinki Fridtjov Hatlebrekke, Volda Hans Hedstrand, Karlstad Niels Henriksen, Gentofte Astradur Hreidarsson, Reykjavik Tuula Huupponen, Tampere Niels Haagensen, Holba;k Bj0rn Heiland, Bergen Jorma Honen, Oulu Jörgen Jakobsson, Göteborg R. Jarrett, London Grethe Finn Jensen, Gentofte Jak Jervell, Oslo Erik Jungersen, R0nne Fritz Sch0nau J0rgensen, Silkeborg Hans j0rgensen, Porsgrunn Kaj R. J0rgensen, Âbenrâ Johannes Kahrs. Fredrikstad Tero Kangas, Vantaa Seppo Karhumaa, Seinäjoki Bent Kjerulf, Gentofte Jens-J0rgen Kjaergaard, Aalborg Seppo Koistinen, Lappeenranta Veikko Koivisto, Helsinki H. P. Ostergaard Kristensen, Slagelse Klaus K0lendorf, K0benhavn Niels A. Larsen, Holstebro Torsten Lauritzen, K0benhavn Thomas Ledet, Arhus Hanna-Liisa Lenko, Tampere Per Lennerhagen, Stockholm E. Lien, Bergen Bo Lindhe, Helsingborg Folke Lithner, Umeä Johnny Ludvigsson, Linköping Rolf Luft, Stockholm Finn Lundegaard, T0nsberg Jens Lyngs0e, K0benhavn Sirkku Mantere, Tampere

6 Timo Martikainen, Mikkeli Cari Erik Mogensen, Ârhus Erik F. Mogensen, Odense Jann Muri, Bod0 Fredrik Mürer. Trondheim Jorma Mäenpää, Helsinki Anna-Liisa Mäkelä, Turku J0rn Nerup, Gentofte Esko Nikkilä, Helsinki Anders Nilsson, Helsingborg Karl Olof Nilsson, Malmö Michael Nissen, Vasa Paul Ohlsén, Danderyd Lave Ohlsson, Skövde Heikki Oksa, Tampere Heikki Oksala, Tampere Kalevi Oksanen, Hämeenlinna Stein Olsson, Hamar Amos Pasternack, Tampere Risto Pelkonen, Helsinki Heikki Pirttiaho, Oulu Timo Pitkäjärvi, Tampere Elja Pitkänen, Helsinki Tuula Pulii, Tampere Marja Puomio, Tampere Kalevi Pyörälä, Kuopio Pentti Reissell, Helsinki Kaj Rosenqvist, Visby Ulf Rosenqvist, Oskarshamn Leena Ryysy, Kotka Uffe Sagild, Vejle Pasi Salmela, Oulu Jorma Salmi, Tampere Timo Sane, Helsinki Pentti Seppälä, Turku Leif Sestoft, K0benhavn Kjartan Seyer-Hansen, Svendborg Onni Siitonen, Kuopio Terje Sindre, Flor0 Anders Sjöholm, Hässleholm Eystein Skaga, Oslo Eero Sotaniemi, Oulu Jan Spjuth, Karlskrona Gunnar Stenström, Göteborg Poul Strunge, Horsens Hâkon Strömblad, Karlsbamn Petter Syse, Lillehammer Niels Schwartz S0rensen, Arhus Ole Tenstad, H0nefoss Birgitta Therman, Helsinki Arni Thorsson, Reykjavik Gunnar Tornvall, Stockholm Timo Tulokas, Rovaniemi Torsten Tuvemo, Uppsala Matti Uusitupa, Kuopio Teppo Vapaavalta, Helsinki Jorma Viikari, Turku Lasse Viinikka, Oulu Jarmo Visakorpi, Tampere Niels Werner, Halmstad Otto Westphal, Göteborg Kaj Wildenhoff, Skanderborg Hannele Yki-Järvinen, Helsinki Kjell Ytrehus, Molde Jan Ostman, Huddinge